Article
Imaging neural activity using Thy1-GCaMP transgenic mice.
Neuron - 18 Oct 2012
Chen Qian, Cichon Joseph, Wang Wenting, Qiu Li, Lee Seok-Jin R, Campbell Nolan R, Destefino Nicholas, Goard Michael J, Fu Zhanyan, Yasuda Ryohei, Looger Loren L, Arenkiel Benjamin R, Gan Wen-Biao, Feng Guoping
Abstract excerpt
The ability to chronically monitor neuronal activity in the living brain is essential for understanding the organization and function of the nervous system. The genetically encoded green fluorescent protein-based calcium sensor GCaMP provides a powerful tool for detecting calcium transients in neuronal somata, processes, and synapses that are triggered by neuronal activities. Here we report the generation and...
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