Article
Dual contribution of NR2B subunit of NMDA receptor and SK3 Ca(2+)-activated K+ channel to genetic predisposition to anorexia nervosa.
Journal of psychiatric research - 1 Jan 2000
Koronyo-Hamaoui Maya, Frisch Amos, Stein Daniel, Denziger Yardena, Leor Shani, Michaelovsky Elena, Laufer Neil, Carel Cynthia, Fennig Silvana, Mimouni Mark, Ram Anca, Zubery Eynat, Jeczmien Pablo, Apter Alan, Weizman Abraham, Gak Eva
Abstract excerpt
Since identification of the genetic component in anorexia nervosa (AN), genes that partake in serotonergic and dopaminergic systems and in hormonal and weight regulation have been suggested as potential candidates for AN susceptibility. We propose another set of candidate genes. Those are genes that are involved in the signaling pathway using NMDA-R and SK channels and have been suggested as possible effectors of...
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