Article
Genetic findings in schizophrenia patients related to alterations in the intracellular Ca-homeostasis.
Progress in neuro-psychopharmacology & biological psychiatry - 1 Dec 2010
Giegling Ina, Genius Just, Benninghoff Jens, Rujescu Dan
Abstract excerpt
There is a relatively high genetic heritability of schizophrenia as shown by family, twin and adoption studies. A large number of hypotheses on the causes of schizophrenia occurred over time. In this review we focus on genetic findings related to potential alterations of intracellular Ca-homeostasis in association with schizophrenia. First, we provide evidence for the NMDA/glutamatergic theory of schizophrenia...
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