Article
CAG repeat polymorphism within the KCNN3 gene is a significant contributor to susceptibility to anorexia nervosa: a case-control study of female patients and several ethnic groups in the Israeli Jewish population.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Nov 2004
Koronyo-Hamaoui Maya, Gak Eva, Stein Daniel, Frisch Amos, Danziger Yardena, Leor Shani, Michaelovsky Elena, Laufer Neil, Carel Cynthia, Fennig Silvana, Mimouni Marc, Apter Alan, Goldman Boleslav, Barkai Gad, Weizman Abraham
Abstract excerpt
The human small-conductance Ca(2+)-activated potassium channel gene KCNN3 has been involved in mechanisms underlying neuronal function and plasticity. A multiallelic CAG repeat polymorphism within the KCNN3 has been associated with schizophrenia and bipolar disorder. We have previously reported in a family-based study that longer CAG repeats are preferentially transmitted to patients with anorexia nervosa (AN)....
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