Article
A piece in the puzzle: an ion channel candidate gene for schizophrenia.
Molecular medicine today - 1 Dec 1998
Gargus J J, Fantino E, Gutman G A
Abstract excerpt
Mutations in ion channels have been found to cause a variety of mendelian genetic diseases, and polyglutamine repeat expansion is a newly recognized pathogenic mechanism that causes several rare, genetic, late-onset neurological syndromes. Polymorphic polyglutamine tracts are present in a recentl...
Topics
- Alleles
- Amino Acid Sequence
- Bipolar Disorder
- Calcium
- Drug Design
- Humans
- Molecular Sequence Data
- Polyglutamic Acid
- Potassium Channels
- Receptors, N-Methyl-D-Aspartate
- Schizophrenia
- Trinucleotide Repeats