Article
Genetic polymorphism of N-acetyltransferase 2 in the susceptibility to laryngeal squamous cell carcinoma.
Head & neck - 1 Dec 2005
Unal Murat, Tamer Lülüfer, Akbaş Yücel, Pata Yavuz Selim, Vayisoglu Yusuf, Degirmenci Ulaş, Camdeviren Handan
Abstract excerpt
BACKGROUND: The purpose of this study was to investigate whether polymorphism of N-acetyltransferase 2 (NAT2) genotypes are associated with the risk of laryngeal squamous cell carcinoma (SCC). METHODS: The study group consisted of 45 white patients with laryngeal SCC (42 men, with a mean age of 54 years [range, 37-70 years] and three women, with a mean age of 47 years [range, 32-55 years]) and 104 control...
Topics
- Adult
- Aged
- Arylamine N-Acetyltransferase
- Carcinoma, Squamous Cell
- Case-Control Studies
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Laryngeal Neoplasms
- Male
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic
