N-acetyltransferase 1 and 2 gene sequence variants and risk of head and neck cancer.

doi:10.1007/s11033-009-9905-8

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Article

N-acetyltransferase 1 and 2 gene sequence variants and risk of head and neck cancer.

Molecular biology reports - 1 Oct 2010

Demokan Semra, Suoglu Yusufhan, Gözeler Mustafa, Demir Deniz, Dalay Nejat

Abstract excerpt

Polymorphisms that alter the function of genes involved in the activation or detoxification of carcinogenic compounds can influence an individuals risk of developing cancer. Polymorphic changes modulating the acetylation capacity of the N-acetyltransferase (NAT) genes have been implicated in the risk of developing cancer. In this study the role of genetically determined individual NAT1 and NAT2 genotypes,...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Alleles
Arylamine N-Acetyltransferase
Base Sequence
Case-Control Studies
Child
Female
Genetic Predisposition to Disease
Haplotypes
Head and Neck Neoplasms
Humans
Isoenzymes
Linkage Disequilibrium
Male
Middle Aged

Source

Open in PubMed

Identifiers

PMID: 19898993
DOI: 10.1007/s11033-009-9905-8

Genes

NAT1
NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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