Article
Differential Global Gene Expression Response Patterns of Human Endothelium Exposed to Shear Stress and Intraluminal Pressure
1 Jan 2005
Abstract excerpt
We investigated the global gene expression response of endothelium exposed to shear stress and intraluminal pressure and tested the hypothesis that the two biomechanical forces induce a differential gene expression response pattern. Intact living human conduit vessels (umbilical veins) were exposed to normal or high intraluminal pressure, or to low or high shear stress in combination with a physiological level of...
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