Article
A null mutation for Fmr1 in female mice: effects on regional cerebral metabolic rate for glucose and relationship to behavior.
Neuroscience - 1 Jan 2005
Qin M, Kang J, Smith C Beebe
Abstract excerpt
As a measure of functional activity we determined regional cerebral metabolic rate for glucose (rCMR(glc)) in adult, female wild type and fragile X (Fmr1 null) mice homozygous and heterozygous for the null mutation. To ascertain if the sexes differ with respect to the severity of the effects of the mutation we compared our results with results of our previous study on male Fmr1 null mice [Qin M, Kang J, Smith CB...
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