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Article

Deletion of Fmr1 results in sex-specific changes in behavior.

Brain and behavior - 1 Oct 2017

Nolan Suzanne O, Reynolds Conner D, Smith Gregory D, Holley Andrew J, Escobar Brianna, Chandler Matthew A, Volquardsen Megan, Jefferson Taylor, Pandian Ashvini, Smith Tileena, Huebschman Jessica, Lugo Joaquin N

Abstract excerpt

OBJECTIVE: In this study, we used a systemic Fmr1 knockout in order to investigate both genotype- and sex-specific differences across multiple measures of sociability, repetitive behaviors, activity levels, anxiety, and fear-related learning and memory. BACKGROUND: Fragile X syndrome is the most common monogenic cause of intellectual disability and autism. Few studies to date have examined sex differences in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fragile X Mental Retardation Protein

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Source

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Identifiers

PMID: 29075560
DOI: 10.1002/brb3.800
PMCID: PMC5651384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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