Article
Wild-type male offspring of fmr-1+/- mothers exhibit characteristics of the fragile X phenotype.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2008
Zupan Bojana, Toth Miklos
Abstract excerpt
Fragile X syndrome is an X-linked disorder caused by the inactivation of the FMR-1 gene with symptoms ranging from impaired cognitive functions to seizures, anxiety, sensory abnormalities, and hyperactivity. Males are more severely affected than heterozygote (H) females, who, as carriers, have a...
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