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Article

Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice.

The Biochemical journal - 1 Jan 2006

Nisenberg Oleg, Pegg Anthony E, Welsh Patricia A, Keefer Kerry, Shantz Lisa M

Abstract excerpt

The present study was designed to provide a better understanding of the role played by AdoMetDC (S-adenosylmethionine decarboxylase), the key rate-controlling enzyme in the synthesis of spermidine and spermine, in controlling polyamine levels and the importance of polyamines in cardiac physiology. The alphaMHC (alpha-myosin heavy chain) promoter was used to generate transgenic mice with cardiac-specific...

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Identifiers

PMID: 16153183
DOI: 10.1042/BJ20051196
PMCID: PMC1383688

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Source receipt: pubmed, retrieved 7 Sept 2026.

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