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Article

Ddb1 controls genome stability and meiosis in fission yeast.

Genes & development - 1 Apr 2005

Holmberg Christian, Fleck Oliver, Hansen Heidi A, Liu Cong, Slaaby Rita, Carr Antony M, Nielsen Olaf

Abstract excerpt

The human UV-damaged DNA-binding protein Ddb1 associates with cullin 4 ubiquitin ligases implicated in nucleotide excision repair (NER). These complexes also contain the signalosome (CSN), but NER-relevant ubiquitination targets have not yet been identified. We report that fission yeast Ddb1, Cullin 4 (Pcu4), and CSN subunits Csn1 and Csn2 are required for degradation of the ribonucleotide reductase (RNR)...

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Identifiers

PMID: 15805471
DOI: 10.1101/gad.329905
PMCID: PMC1074322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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