Article
Sem1p is a novel subunit of the 26 S proteasome from Saccharomyces cerevisiae.
The Journal of biological chemistry - 2 Jul 2004
Sone Takayuki, Saeki Yasushi, Toh-e Akio, Yokosawa Hideyoshi
Abstract excerpt
The 26 S proteasome, which catalyzes degradation of polyubiquitinated proteins, is composed of the 20 S proteasome and the 19 S regulatory particle (RP). The RP is composed of the lid and base subcomplexes and regulates the catalytic activity of the 20 S proteasome. In this study, we carried out affinity purification of the lid and base subcomplexes from the tagged strains of Saccharomyces cerevisiae, and we...
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