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Article

Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2005

Zhang Tianyi, Tran Susan, Clouser Christopher, Pignoni Francesca

Abstract excerpt

Nicastrin is a component of the Notch signaling pathway involved in proteolytic release of the Notch receptor intracellular domain. It has been postulated that intracellular Notch is required within the nucleus of fly eye progenitor cells to enhance (pro-neural enhancement) and then repress (lateral inhibition) transcription of pro-neural genes. We present here an analysis of Nicastrin function during eye...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 16145661
DOI: 10.1002/dvdy.20543

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye.PMID 16145661Read ↗

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