Article
Notch-Delta signaling is required for spatial patterning and Müller glia differentiation in the zebrafish retina.
Developmental biology - 15 Feb 2005
Bernardos R L, Lentz S I, Wolfe M S, Raymond P A
Abstract excerpt
Notch-Delta signaling has been implicated in several alternative modes of function in the vertebrate retina. To further investigate these functions, we examined retinas from zebrafish embryos in which bidirectional Notch-Delta signaling was inactivated either by the mind bomb (mib) mutation, which disrupts E3 ubiquitin ligase activity, or by treatment with gamma-secretase inhibitors, which prevent intramembrane...
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