Article
Comparative genomic hybridization array analysis and real time PCR reveals genomic alterations in squamous cell carcinomas of the lung.
Lung cancer (Amsterdam, Netherlands) - 1 Jan 2007
Choi Yong-Woo, Choi Jin Soo, Zheng Long Tai, Lim Yun Jeong, Yoon Hyoung Kyu, Kim Yeul Hong, Wang Young-Pil, Lim Young
Abstract excerpt
Genomic alterations have been identified in lung cancer tissues and reported in numerous studies. To analyze genomic aberrations in lung cancer patients, we used array comparative genomic hybridization (array CGH) in 14 squamous cell lung carcinoma (SqC) tissues. Copy number gain and loss in chromosomal regions were detected, and the corresponding genes were confirmed by real time PCR. Several frequently altered...
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