Article
Genomic approaches to lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jul 2006
Thomas Roman K, Weir Barbara, Meyerson Matthew
Abstract excerpt
The last decade has seen remarkable success in clinical targeting of activated oncogenes in cancer. We have applied gene expression profiling, high-density single-nucleotide polymorphism arrays, and systematic resequencing of genes to identify novel oncogenes and signaling pathways in lung cancer that might represent therapeutic targets. Systematic resequencing of tyrosine kinase genes has led to the discovery of...
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