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Article

BRAF mutation in endometrial carcinoma and hyperplasia: correlation with KRAS and p53 mutations and mismatch repair protein expression.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2005

Feng Yu-Zhen, Shiozawa Tanri, Miyamoto Tsutomu, Kashima Hiroyasu, Kurai Miyuki, Suzuki Akihisa, Konishi Ikuo

Abstract excerpt

PURPOSE: Although several gene abnormalities have been reported in endometrial carcinoma, the genetic alterations have not fully been elucidated. Recent studies have revealed frequent activating mutations of the gene for BRAF, an effector of Ras protein in the mitogen-activated protein kinase pathway, in several malignancies. However, the prevalence and significance of BRAF mutations in endometrial carcinoma...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16144912
DOI: 10.1158/1078-0432.CCR-04-2670

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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