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Mismatch Repair Deficiency in Endometrial Cancer: Immunohistochemistry Staining and Clinical Implications

25 Sept 2019

Abstract excerpt

INTRODUCTION: DNA mismatch repair (MMR) deficiency is associated with increased risk of developing several types of cancer and is the most common cause of hereditary endometrial cancer. Identification of the microsatellite instability (MSI) phenotype in endometrial carcinoma is important given that such tumors are frequent. OBJECTIVE: The objective of this study was to assess the utility of immunohistochemistry...

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PMID: 31567138
DOI: 10.1097/pai.0000000000000641

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