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Article

Carcinogenic mechanisms of endometrial cancer: involvement of genetics and epigenetics.

The journal of obstetrics and gynaecology research - 1 Aug 2014

Banno Kouji, Yanokura Megumi, Iida Miho, Masuda Kenta, Aoki Daisuke

Abstract excerpt

Endometrial cancer is increasing worldwide and the number of patients with this disease is likely to continue to grow, including younger patients. Many endometrial cancers show estrogen-dependent proliferation, but the carcinogenic mechanisms are unknown or not completely explained beyond mutations of single oncogenes and tumor suppressor genes. Possible carcinogenic mechanisms include imbalance between...

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Topics

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Share to Carcinogenesis
Share to Cell Transformation, Neoplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

Share to Endometrial Neoplasms

Share to Endometrium

Share to Epigenesis, Genetic

Share to Gene Silencing

Share to Microsatellite Instability

Source

Identifiers

PMID: 25131761
DOI: 10.1111/jog.12442

Genes

CDH1
CHFR
PTEN
SPRY2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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