Article
Reduced prepulse inhibition of startle in STAT6-deficient mice.
International journal of molecular medicine - 1 Oct 2005
Yukawa Kazunori, Tanaka Tetsuji, Owada-Makabe Kyoko, Tsubota Yuji, Bai Tao, Maeda Masanobu, Takeda Kiyoshi, Akira Shizuo, Iso Hiroyuki
Abstract excerpt
To determine the role of STAT6 transcription factors in brain function, we performed a battery of mouse behavioral analyses of STAT6-deficient mice. We recently showed that STAT6-deficient mice displayed increased locomotor activities and had reduced levels of dopamine transporter (DAT) expression in the striatum. To further examine the behavioral effects of STAT6 deficiency, we subjected STAT6-deficient mice to...
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