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Article

Latency to startle is increased in the 5xFAD mouse model of Alzheimer’s disease.

Behavioural brain research - 1 Feb 2019

Story Darren, Chan Emily, Munro Nikolas, Rossignol Julien, Dunbar Gary L

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that results in cognitive decline and a number of other neuropsychiatric symptoms. One area that is often affected by neuropsychiatric disease is the response to sudden, loud noises, as measured by the acoustic startle response (ASR), and prepulse inhibition (PPI), which indicates sensory-gating abilities. Evidence suggests AD patients, even...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30055208
DOI: 10.1016/j.bbr.2018.07.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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