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Article

<i>Shox2</i>-deficient mice exhibit a rare type of incomplete clefting of the secondary palate

3 Sept 2005

Abstract excerpt

The short stature homeobox gene SHOX is associated with idiopathic short stature in humans, as seen in Turner syndrome and Leri-Weill dyschondrosteosis, while little is known about its close relative SHOX2. We report the restricted expression of Shox2 in the anterior domain of the secondary palate in mice and humans. Shox2-/- mice develop an incomplete cleft that is confined to the anterior region of the palate,...

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Identifiers

PMID: 16141225
DOI: 10.1242/dev.02013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

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Research trail→

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<i>Shox2</i>-deficient mice exhibit a rare type of incomplete clefting of the secondary palatePMID 16141225Read ↗

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Replacing Shox2 with human SHOX leads to congenital disc degeneration of the temporomandibular joint in miceSemantic proximity Read ↗

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