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Article

Mice with an anterior cleft of the palate survive neonatal lethality.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 May 2008

Gu Shuping, Wei Na, Yu Xueyan, Jiang Yiping, Fei Jian, Chen YiPing

Abstract excerpt

Many genes are known to function in a region-specific manner in the developing secondary palate. We have previously shown that Shox2-deficient embryos die at mid-gestation stage and develop an anterior clefting phenotype. Here, we show that mice carrying a conditional inactivation of Shox2 in the palatal mesenchyme survive the embryonic and neonatal lethality, but develop a wasting syndrome. Phenotypic analyses...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 18393307
DOI: 10.1002/dvdy.21534
PMCID: PMC3010755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mice with an anterior cleft of the palate survive neonatal lethality.PMID 18393307Read ↗

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