Article
Analysis of Meox-2 mutant mice reveals a novel postfusion-based cleft palate.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2006
Jin Jiu-Zhen, Ding Jixiang
Abstract excerpt
Cleft palate represents a common human congential disease involving defects in the development of the secondary palate. Major steps in mammalian palatogenesis include vertical growth, elevation, and fusion of the palate shelves. Our current study with the homeobox gene Meox-2 during mouse secondary palate development reveals a novel postfusion-based mechanism for cleft palate. Meox-1 and Meox-2 are two...
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