Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Deletion or substitution of the aphthovirus 3′ NCR abrogates infectivity and virus replication

1 Jan 2001

Abstract excerpt

The 3' noncoding region (NCR) of the genomic picornaviral RNA is believed to contain major cis-acting signals required for negative-strand RNA synthesis. The 3' NCR of foot-and-mouth disease virus (FMDV) was studied in the context of a full-length infectious clone in which the genetic element was deleted or exchanged for the equivalent region of a distantly related swine picornavirus, swine vesicular disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Animal Virus Infections Studies
Share to Viral Infections and Immunology Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11125162
DOI: 10.1099/0022-1317-82-1-93

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Deletion or substitution of the aphthovirus 3′ NCR abrogates infectivity and virus replicationPMID 11125162Read ↗

An authentic 3' noncoding region is necessary for efficient poliovirus replication.Semantic proximity Read ↗

The 3' untranslated region of picornavirus RNA: features required for efficient genome replicationSemantic proximity Read ↗

IRES-driven translation is stimulated separately by the FMDV 3'-NCR and poly(A) sequencesSemantic proximity Read ↗

The RNA pseudoknots in foot-and-mouth disease virus are dispensable for genome replication but essential for the production of infectious virusSemantic proximity Read ↗

Kissing Interaction between 3′ Noncoding and Coding Sequences Is Essential for Porcine Arterivirus RNA ReplicationSemantic proximity Read ↗

The 5'-untranslated regions of picornavirus RNAs contain independent functional domains essential for RNA replication and translationSemantic proximity Read ↗

Similar interactions of the poliovirus and rhinovirus 3D polymerases with the 3' untranslated region of rhinovirus 14.Semantic proximity Read ↗

Mutagenesis Mapping of RNA Structures within the Foot-and-Mouth Disease Virus Genome Reveals Functional Elements Localised in the Polymerase (3D <sup>pol</sup> ) Encoding RegionSemantic proximity Read ↗

Large deletions in the 5′-untranslated region of foot-and-mouth disease virus of serotype CSemantic proximity Read ↗

Cytopathogenic and Noncytopathogenic RNA Replicons of Classical Swine Fever VirusSemantic proximity Read ↗

Identification and Characterization of a <i>cis</i> -Acting Replication Element ( <i>cre</i> ) Adjacent to the Internal Ribosome Entry Site of Foot-and-Mouth Disease VirusSemantic proximity Read ↗

The 3′ <i>cis</i> -Acting Genomic Replication Element of the Severe Acute Respiratory Syndrome Coronavirus Can Function in the Murine Coronavirus GenomeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.