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Article

The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication

1 Dec 1998

Abstract excerpt

Cis-acting RNA signals are required for replication of positive-strand viruses such as the picornaviruses. Although these generally have been mapped to the 5' and/or 3' termini of the viral genome, RNAs derived from human rhinovirus type 14 are unable to replicate unless they contain an internal cis-acting replication element (cre) located within the genome segment encoding the capsid proteins. Here, we show that...

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PMID: 9848654
DOI: 10.1017/s1355838298981006

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