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Article

A coding RNA sequence acts as a replication signal in cardioviruses

28 Sept 1999

Abstract excerpt

Theiler's virus and Mengo virus are representatives of the Cardiovirus genus within the picornavirus family. Their genome is an 8-kilobase long positive strand RNA molecule. This RNA molecule plays three roles in infected cells: It serves as a messenger RNA, acts as a template for genome replication, and is encapsidated to form progeny virions. We observed that a cis-acting signal required for replication of...

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PMID: 10500216
DOI: 10.1073/pnas.96.20.11560

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