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Coronavirus Replication: Genomes, Subgenomic RNAs, and Defective Viral Genomes

28 May 2025

Abstract excerpt

With the emergence of the SARS-CoV-2 pandemic the process of coronavirus replication has been under increasing scrutiny. During the replication of their genomic RNA, coronaviruses produce a range of other RNAs in addition to the negative-sense replicative intermediates of the genome, which includes a set of subgenomic RNAs. These subgenomic RNAs are nested within the sequence of the complete genome and can be...

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PMID: 40573357
DOI: 10.3390/v17060767

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