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Article

NTE/PNPLA6 is expressed in mature Schwann cells and is required for glial ensheathment of Remak fibers.

Glia - 1 May 2017

McFerrin Janis, Patton Bruce L, Sunderhaus Elizabeth R, Kretzschmar Doris

Abstract excerpt

Neuropathy target esterase (NTE) or patatin-like phospholipase domain containing 6 (PNPLA6) was first linked with a neuropathy occurring after organophosphate poisoning and was later also found to cause complex syndromes when mutated, which can include mental retardation, spastic paraplegia, ataxia, and blindness. NTE/PNPLA6 is widely expressed in neurons but experiments with its Drosophila orthologue...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28206686
DOI: 10.1002/glia.23127
PMCID: PMC5357176

Genes

PNPLA6
GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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NTE/PNPLA6 is expressed in mature Schwann cells and is required for glial ensheathment of Remak fibers.PMID 28206686Read ↗

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