Article
Three-dimensional structure of a recombinant variant of human pancreatic secretory trypsin inhibitor (Kazal type).
Journal of molecular biology - 20 Jun 1992
Hecht H J, Szardenings M, Collins J, Schomburg D
Abstract excerpt
A modified version of the human pancreatic trypsin inhibitor (PSTI), generated in a protein-design project, has been crystallized in spacegroup P4(3) with lattice constants a = 40.15 A, c = 33.91 A. The structure has been solved by molecular replacement. Refinement of the structure by simulated annealing and conventional restrained least-squares yielded for 8.0 to 2.3 A data a final R-value of 19.1%. Differences...
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