Article
SULT1A1 polymorphism and esophageal cancer in males.
International journal of cancer - 1 Jan 2003
Wu Ming-Tsang, Wang Yi-Ting, Ho Chi-Kung, Wu Deng-Chyang, Lee Yung-Chie, Hsu Hon-Ki, Kao Ein-Long, Lee Jang-Ming
Abstract excerpt
Sulfotransferase (SULT) 1A1 detoxifies and bioactivates a broad spectrum of substrates including xenobiotics. It has been suggested that the SULT1A1 his (histidine) allele, which is caused by a his for arg (arginine) substitution due to a G-->A transition at codon 213, carries a significantly higher risk for women to develop breast cancer. We investigated the association between the SULT1A1 arg/his genotype and...
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