Article
Methylenetetrahydrofolate reductase polymorphisms and the risk of gestational hypertension.
Epidemiology (Cambridge, Mass.) - 1 Sept 2005
Hernández-Díaz Sonia, Wu Xiao F, Hayes Catherine, Werler Martha M, Ashok Tara Devi S, Badovinac Rachel, Kelsey Karl T, Mitchell Allen A
Abstract excerpt
BACKGROUND: Evidence on the association of 5,10 methylentetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms in women with gestational hypertension is inconsistent. It is also unknown whether the fetal genotype is relevant, or whether folic acid supplementation modifies this association. METHODS: The study population was composed of U.S. and Canadian white women with nonmalformed infants...
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