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Article

Infant C677T MTHFR polymorphism and severe mental retardation.

Birth defects research. Part A, Clinical and molecular teratology - 1 Jan 2007

Shaw Gary M, Jelliffe-Pawlowski Laura, Nelson Verne, Zhu Huiping, Harris John A, Finnell Richard H

Abstract excerpt

BACKGROUND: We investigated whether infants with homozygous genotype TT of the MTHFR gene were at increased risk of severe mental retardation. METHODS: One hundred children with severe mental retardation (cases) were investigated from a large geographic-based study of infants born in California in 1992-1993. Cases were compared to 743 randomly selected nonmalformed control infants born in California during...

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Source

Identifiers

PMID: 17149733
DOI: 10.1002/bdra.20321

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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