Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional Synergy and the Regulation of <i>Ucp1</i> during Brown Adipocyte Induction in White Fat Depots

31 Aug 2005

Abstract excerpt

Induction of brown adipocytes in white fat depots by adrenergic stimulation is a complex genetic trait in mice that affects the ability of the animal to regulate body weight. An 80-fold difference in expression of the mitochondrial uncoupling gene (Ucp1) at the mRNA and protein levels between A/J and C57BL/6J (B6) mice is controlled by allelic interactions among nine quantitative trait loci (QTLs) on eight...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16135818
DOI: 10.1128/mcb.25.18.8311-8322.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional Synergy and the Regulation of <i>Ucp1</i> during Brown Adipocyte Induction in White Fat DepotsPMID 16135818Read ↗

The Genetics of Brown Adipocyte Induction in White Fat DepotsSemantic proximity Read ↗

Synergistic gene interactions control the induction of the mitochondrial uncoupling protein (Ucp1) gene in white fat tissue.Semantic proximity Read ↗

Targeting PPARγ in the epigenome rescues genetic metabolic defects in miceSemantic proximity Read ↗

Dietary fat interacts with QTLs controlling induction of Pgc-1 alpha and Ucp1 during conversion of white to brown fat.Semantic proximity Read ↗

Transcriptional Regulation of the Mouse Uncoupling Protein-2 GeneSemantic proximity Read ↗

p38 Mitogen-Activated Protein Kinase Is the Central Regulator of Cyclic AMP-Dependent Transcription of the Brown Fat Uncoupling Protein 1 GeneSemantic proximity Read ↗

PPARγ activation by lipolysis-generated ligands is required for cAMP dependent <i>UCP1</i> induction in human thermogenic adipocytesSemantic proximity Read ↗

Uncoupling protein 1-driven Cre ( <i>Ucp1-Cre</i> ) is expressed in the epithelial cells of mammary glands and various non-adipose tissuesSemantic proximity Read ↗

Cannabinoid type 1 receptor blockade induces transdifferentiation towards a brown fat phenotype in white adipocytes.Semantic proximity Read ↗

PPARs in the Control of Uncoupling Proteins Gene ExpressionSemantic proximity Read ↗

Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes.Semantic proximity Read ↗

Trans-10, cis-12 conjugated linoleic acid causes inflammation and delipidation of white adipose tissue in mice: a microarray and histological analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.