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Article

Transcriptional Regulation of the Mouse Uncoupling Protein-2 Gene

1 Apr 2001

Abstract excerpt

Uncoupling protein-2 (UCP2) is present in many tissues with relevance to fuel metabolism, and its expression is increased in fat and muscle in response to elevated circulating free fatty acids resulting from fasting and high fat feeding. We proposed a role for peroxisome proliferator-activated receptor-gamma (PPARgamma) as a mediator of these physiological changes in UCP2, because thiazolidinediones also increase...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 11150307
DOI: 10.1074/jbc.m010587200

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