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Article

PPARs in the Control of Uncoupling Proteins Gene Expression

1 Jan 2007

Abstract excerpt

Uncoupling proteins (UCPs) are mitochondrial membrane transporters involved in the control of energy conversion in mitochondria. Experimental and genetic evidence relate dysfunctions of UCPs with metabolic syndrome and obesity. The PPAR subtypes mediate to a large extent the transcriptional regulation of the UCP genes, with a distinct relevance depending on the UCP gene and the tissue in which it is expressed....

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Identifiers

PMID: 17389766
DOI: 10.1155/2007/74364

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