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Article

Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes.

Molecular and cellular biology - 1 Jul 2005

Robidoux Jacques, Cao Wenhong, Quan Hui, Daniel Kiefer W, Moukdar Fatiha, Bai Xu, Floering Lisa M, Collins Sheila

Abstract excerpt

The sympathetic nervous system regulates the activity and expression of uncoupling protein 1 (UCP1) through the three beta-adrenergic receptor subtypes and their ability to raise intracellular cyclic AMP (cAMP) levels. Unexpectedly, we recently discovered that the cAMP-dependent regulation of mul...

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Source

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Identifiers

PMID: 15964803
DOI: 10.1128/MCB.25.13.5466-5479.2005
PMCID: PMC1157000

Genes

UCP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15964803-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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