Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

New ovine PrP gene haplotypes as a result of single nucleotide polymorphisms in the PrP gene promoter.

Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie - 1 Apr 2005

O'Neill G T, Cairns D, Toovey L, Goldmann W, Hunter N

Abstract excerpt

Incidence of scrapie in sheep is strongly associated with PrP gene amino acid codon variants at positions 136, 154 and 171. However, there are breed differences in disease linkage and anomalous disease patterns which cannot obviously be explained by the '3 codon' genotype. Mouse studies indicate that PrP protein levels can influence scrapie disease progression and this prompted us to study the sheep PrP gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Southern
Share to DNA Primers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Components

Share to Genetic Linkage

Share to Prions

Share to Scrapie

Share to Species Specificity

Source

Identifiers

PMID: 16130475
DOI: 10.1111/j.1439-0388.2005.00520.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

New ovine PrP gene haplotypes as a result of single nucleotide polymorphisms in the PrP gene promoter.PMID 16130475Read ↗

Ovine PRNP untranslated region and promoter haplotype diversity.Semantic proximity Read ↗

Influence of the prion protein gene, Prnp, on scrapie susceptibility in sheep.Semantic proximity Read ↗

Frequency of genotypes in the PrP prion protein gene locus in the Polish sheep population.Semantic proximity Read ↗

Identification of polymorphisms in the ovine Shadow of prion protein (SPRN) gene and assessment of their effect on promoter activity and susceptibility for classical scrapie.Semantic proximity Read ↗

PrP gene polymorphism in sheep breeds in Slovakia and susceptibility to scrapie.Semantic proximity Read ↗

Amino acid polymorphisms of PrP with reference to onset of scrapie in Suffolk and Corriedale sheep in Japan.Semantic proximity Read ↗

Polymorphism of prion protein gene (PRNP) in Nigerian sheep.Semantic proximity Read ↗

Frequencies of PrP gene haplotypes in British sheep flocks and the implications for breeding programmes.Semantic proximity Read ↗

Frequent missense and insertion/deletion polymorphisms in the ovine Shadoo gene parallel species-specific variation in PrP.Semantic proximity Read ↗

Nucleotide variants in prion-related protein (testis-specific) gene (PRNT) and effects on Chinese and Mongolian sheep phenotypes.Semantic proximity Read ↗

Five Novel PRNP Gene Polymorphisms and Their Potential Effect on Scrapie Susceptibility in Three Native Ethiopian Sheep BreedsSemantic proximity Read ↗

Allelic variants of PRNP in 16 Chinese local sheep breeds.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.