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Article

Lack of JunD promotes pressure overload-induced apoptosis, hypertrophic growth, and angiogenesis in the heart.

Circulation - 6 Sept 2005

Hilfiker-Kleiner Denise, Hilfiker Andres, Kaminski Karol, Schaefer Arnd, Park Joon-Keun, Michel Kim, Quint Anja, Yaniv Moshe, Weitzman Jonathan B, Drexler Helmut

Abstract excerpt

BACKGROUND: The Jun family of activator protein 1 (AP-1) transcription factors (c-Jun, JunB, and JunD) is involved in fundamental biological processes such as proliferation, apoptosis, tumor angiogenesis, and hypertrophy. The role of individual AP-1 transcription factors in the stressed heart is not clear. In the present study we analyzed the role of JunD in survival, hypertrophy, and angiogenesis in the...

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Source

Identifiers

PMID: 16129800
DOI: 10.1161/CIRCULATIONAHA.104.518472

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lack of JunD promotes pressure overload-induced apoptosis, hypertrophic growth, and angiogenesis in the heart.PMID 16129800Read ↗

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