Article
Targeted disruption of the murine junD gene results in multiple defects in male reproductive function.
Development (Cambridge, England) - 1 Jan 2000
Thépot D, Weitzman J B, Barra J, Segretain D, Stinnakre M G, Babinet C, Yaniv M
Abstract excerpt
JunD is one of three mammalian Jun proteins that contribute to the AP-1 transcription factor complex. Distinct regulation and functions have been proposed for each Jun member, but less is known about the biological functions of each of these proteins in vivo. To investigate the role of JunD, we have inactivated the murine gene by replacement with a bacterial lacZ reporter gene. Embryonic JunD expression was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
