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Article

Novel genetic variations of the p53R2 gene in patients with colorectal adenoma and controls.

World journal of gastroenterology - 7 Sept 2005

Deng Zong-Lin, Xie Da-Wen, Bostick Roberd M, Miao Xi-Jiang, Gong You-Ling, Zhang Jin-Hui, Wargovich Michael J

Abstract excerpt

AIM: p53-inducible ribonucleotide reductase small subunit 2 (p53R2) encodes a 351-amino-acid peptide, which catalyzes conversion of ribonucleoside diphosphates to the corresponding deoxyribonucleotides required for DNA replication and repair. A recent study reported that a point mutation (G/T) in the p53 binding sequence in a colon cancer cell line completely impaired p53R2 protein activity. METHODS: We screened...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16127747
DOI: 10.3748/wjg.v11.i33.5169
PMCID: PMC4320390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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