Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differentially Regulated Micro-RNAs and Actively Translated Messenger RNA Transcripts by Tumor Suppressor p53 in Colon Cancer

1 Apr 2006

Abstract excerpt

PURPOSE: The aim of this study was to investigate the role of p53 in regulating micro-RNA (miRNA) expression due to its function as a transcription factor. In addition, p53 may also affect other cellular mRNA gene expression at the translational level either via its mediated miRNAs or due to its RNA-binding function. EXPERIMENTAL DESIGN: The possible interaction between p53 and miRNAs in regulating gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to MicroRNA in disease regulation
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16609010
DOI: 10.1158/1078-0432.ccr-05-1853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differentially Regulated Micro-RNAs and Actively Translated Messenger RNA Transcripts by Tumor Suppressor p53 in Colon CancerPMID 16609010Read ↗

The p53-signaling pathway and colorectal cancer: Interactions between downstream p53 target genes and miRNAsSemantic proximity Read ↗

The dichotomy of p53 regulation by noncoding RNAs.Semantic proximity Read ↗

Modulation of microRNA processing by p53.Semantic proximity Read ↗

Non-coding RNAs, guardians of the p53 galaxy.Semantic proximity Read ↗

New features of micro-RNA regulation of mRNA translation and stability revealed by expression of targeted or not targeted reporter genesSemantic proximity Read ↗

MicroRNA-339-5p inhibits colorectal tumorigenesis through regulation of the MDM2/p53 signalingSemantic proximity Read ↗

Multi-level gene expression profiles affected by thymidylate synthase and 5-fluorouracil in colon cancerSemantic proximity Read ↗

An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34aSemantic proximity Read ↗

Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells.Semantic proximity Read ↗

Dysregulation of microRNA biogenesis in cancer: the impact of mutant p53 on Drosha complex activity.Semantic proximity Read ↗

Novel mRNA isoforms and mutations of uridine monophosphate synthetase and 5-fluorouracil resistance in colorectal cancer.Semantic proximity Read ↗

p53 and microRNA-34 are suppressors of canonical Wnt signaling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.