Article
The discovery and confirmation of single nucleotide polymorphisms in the human p53R2 gene by EST database analysis.
Mutagenesis - 1 Sept 2002
Ye Zheng, Parry James M
Abstract excerpt
The human expressed sequence tag (EST) database provides a wealth of resources, which can be used to rapidly screen for potential polymorphisms in proteins of physiological interest. The human p53R2 gene, a recently identified ribonucleotide reductase, plays an important role in DNA repair and is involved in the pathway of p53 activity in response to the presence of DNA damage. On the basis of the alignment of...
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