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Article

p53 Arg72Pro polymorphism and risk of colorectal adenoma and cancer.

International journal of cancer - 15 Oct 2006

Koushik Anita, Tranah Gregory J, Ma Jing, Stampfer Meir J, Sesso Howard D, Fuchs Charles S, Giovannucci Edward L, Hunter David J

Abstract excerpt

A single nucleotide polymorphism (SNP) at codon 72 of the p53 gene (Arg72Pro) alters the p53 protein structure and affects its activity. We investigated this SNP in relation to colorectal adenoma and cancer among men and women from case-control studies nested within the Nurses' Health Study, the Health Professionals Follow-up Study and the Physicians' Health Study. Among 856 colorectal adenoma cases and 1,184...

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Identifiers

PMID: 16721787
DOI: 10.1002/ijc.22057

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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