Article
New approaches for genotyping paraffin wax embedded breast tissue from patients with cancer: the Iowa women's health study.
Journal of clinical pathology - 1 Sept 2005
Thyagarajan B, Anderson K E, Kong F, Selk F R, Lynch C F, Gross M D
Abstract excerpt
BACKGROUND: The use of paraffin wax embedded tissue samples as a source of DNA for genotype analysis has been limited because of difficulties in DNA extraction and single nucleotide polymorphism (SNP) analysis. AIMS: To test the feasibility of applying the combination of a commonly used DNA isolation procedure, PureGene, and a high throughput SNP analysis method, the polymerase chain reaction (PCR)-INVADER assay,...
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