Article
A frequent toll-like receptor (TLR)-2 polymorphism is a risk factor for coronary restenosis.
Journal of molecular medicine (Berlin, Germany) - 1 Jun 2005
Hamann Lutz, Gomma Abuzeid, Schröder Nicolas W J, Stamme Cordula, Glaeser Christiane, Schulz Susanne, Gross Michael, Anker Stefan D, Fox Kim, Schumann Ralf R
Abstract excerpt
Restenosis is a major problem for patients undergoing percutaneous transluminal coronary angioplasty (PTCA). Inflammatory processes and genetic factors have been suggested to be involved in the pathogenesis of both atherosclerosis and restenosis. The recently discovered family of Toll-like receptors (TLRs) consists of molecules that initiate signaling after host-pathogen interactions. Recently it has been shown...
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