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Article

Aminoglycoside antibiotics induce bacterial biofilm formation.

Nature - 25 Aug 2005

Hoffman Lucas R, D'Argenio David A, MacCoss Michael J, Zhang Zhaoying, Jones Roger A, Miller Samuel I

Abstract excerpt

Biofilms are adherent aggregates of bacterial cells that form on biotic and abiotic surfaces, including human tissues. Biofilms resist antibiotic treatment and contribute to bacterial persistence in chronic infections. Hence, the elucidation of the mechanisms by which biofilms are formed may assist in the treatment of chronic infections, such as Pseudomonas aeruginosa in the airways of patients with cystic...

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Identifiers

PMID: 16121184
DOI: 10.1038/nature03912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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