Article

Identification of echinacoside as a tobramycin potentiator against <i>Pseudomonas aeruginosa</i> aggregates

2024-02-09

Abstract excerpt

Cyclic diguanylate (c-di-GMP) is a central biofilm regulator, where increased intracellular levels promote biofilm formation and antibiotic tolerance. Targeting the c-di-GMP network is a promising anti-biofilm approach. Most agents reported previously decreased c-di-GMP to eliminate surface-attached biofilms, which did not recapitulate in vivo biofilms well and may thus impede their clinical impact. Here, the exp...

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Literature Corpus work: 86390496-f992-5cbf-8a59-621ef727b7fb
DOI: 10.1101/2024.02.09.579617

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